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Translocation (12;14)(q13;q32) in myelodysplastic syndrome
L Badía1, M A Alvarez, F Palau
1Unidad de Genética Hospital Universitario La Fe, Valencia, Spain.
Cancer Genetics and Cytogenetics
|January 1, 1993
Abstract:
We report a patient diagnosed with refractory anemia with excess blasts in transformation (RAEB-t) who underwent an evolution to a nonlymphocytic acute leukemia (ANLL-M5a). Initial cytogenetic study showed a diploid karyotype; however, when ANLL-M5a was diagnosed, the bone marrow (BM) cells showed a t(12;14)(q13;q32), which to our knowledge has not been described previously in a myelodysplastic syndrome (MDS).