Related Experiment Video
Updated: Aug 10, 2026

Visualization of Vascular and Parenchymal Regeneration after 70% Partial Hepatectomy in Normal Mice
Published on: September 13, 2016
Splenic and partial hepatic necrosis after vascular occlusion
N K Lee1, J J Sziklas, R P Spencer
1Department of Nuclear Medicine, University of Connecticut Health Center, Farmington, Connecticut 06030-2935.
Abstract:
A 74-year-old woman underwent two operations to correct an aortoduodenal fistula and to have an axillofemoral bypass graft inserted; these required temporary vascular occlusion. Her hepatic function test results began deteriorating. Initial and follow-up Tc-99m sulfur colloid studies revealed activity in the kidneys, consistent with disseminated intravascular coagulation. There was significant radiocolloid in the bone marrow and lungs, suggesting severe hepatic dysfunction. The spleen was not demonstrable on dynamic images or static views. In addition, there was a significant lateral hepatic defect, with a "lung overlap." The splenic lack of function and the hepatic lesion were due to necrosis (demonstrable on CT imaging), likely related to the prior vascular clamping.
More Related Videos
Related Concept Videos
Ischemic Stroke ll: Pathophysiology
Hemorrhagic Stroke ll: Pathophysiology

