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Related Concept Videos

Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...

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Related Experiment Video

Updated: May 9, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 17, 2013

Perforation from endoscopic small bowel biopsy

B Scott1, G Holmes

  • 1Department of Medicine, Lincoln County Hospital.

Gut
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Endoscopic small bowel biopsy can lead to duodenal perforation. While one patient required surgery for their perforation, another with celiac disease recovered with conservative care.

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Related Experiment Videos

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Area of Science:

  • Gastroenterology
  • Surgical Procedures
  • Gastrointestinal Endoscopy

Background:

  • Endoscopic procedures, including small bowel biopsy, are common diagnostic tools.
  • Complications from endoscopy, though rare, can be serious.
  • Small bowel biopsies aim to diagnose conditions like celiac disease.

Observation:

  • Two patients developed duodenal perforation following seemingly routine endoscopy with small bowel biopsy.
  • One patient had normal small bowel mucosa.
  • The other patient was diagnosed with celiac disease.

Findings:

  • A patient with normal small bowel mucosa required surgical intervention (laparotomy and suturing) for duodenal perforation.
  • A patient with celiac disease experienced resolution of their duodenal perforation with conservative management.

Implications:

  • This highlights the potential risk of perforation associated with small bowel biopsies, even when seemingly straightforward.
  • It suggests that the underlying condition (e.g., celiac disease) might influence the management and outcome of iatrogenic perforations.
  • Further investigation into risk factors and management strategies for endoscopic duodenal perforations is warranted.