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Related Experiment Videos

Progressive focal deficit with porencephaly

W R Leahy, H S Singer

    Archives of Neurology
    |March 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Porencephalic cysts and hydrocephalus can cause progressive neurological deficits. Neurosurgical intervention improved symptoms in four patients with this condition.

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    Area of Science:

    • Neurology
    • Neurosurgery
    • Pediatric Neurology

    Background:

    • The association between porencephalic cysts and hydrocephalus has been documented since 1939.
    • Previous reports often described this combination as causing fixed, nonprogressive neurological issues.

    Observation:

    • This study details four patients with hydrocephalus experiencing progressive focal motor deficits.
    • These deficits were attributed to porencephalic diverticulation of the lateral ventricle.
    • Increased intracranial pressure was not a universal symptom across all patients.

    Findings:

    • Enlargement of porencephalic cysts appears linked to increased intraventricular pressure or independent hydrostatic forces.
    • Computerized axial tomography (CAT) enabled noninvasive definition and monitoring of the abnormality's progression.

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  • All studied patients demonstrated clinical improvement following neurosurgical intervention.

    • Implications:

    • This research highlights a treatable cause of progressive neurological deficits in patients with hydrocephalus and porencephalic cysts.
    • Early diagnosis and intervention, aided by advanced imaging techniques like CAT, are crucial.
    • Neurosurgical management offers a viable therapeutic option for improving patient outcomes.