Safety and immunogenicity of Salmonella typhi Ty21a vaccine in young Thai children
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S J Cryz1, N Vanprapar, U Thisyakorn
1Swiss Serum and Vaccine Institute, Berne.
Infection and Immunity
|March 1, 1993
Abstract:
Salmonella typhi Ty21a vaccine in a liquid formulation was evaluated in 634 Thai children 2 to 6 years of age. The seroconversion rate was 69% for those who received vaccine versus 14% for those who received placebo (P < 0.005). The immune responses among vaccine recipients ranged from 60% in 3-year-olds to 81% for 6-year-olds.