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Related Experiment Videos

Apple juice malabsorption: fructose or sorbitol?

J H Hoekstra1, A A van Kempen, C M Kneepkens

  • 1Department of Paediatrics, Groot Ziekengasthuis, 's-Hertogenbosch, Amsterdam, The Netherlands.

Journal of Pediatric Gastroenterology and Nutrition
|January 1, 1993
PubMed
Summary

Apple juice malabsorption, causing diarrhea, is primarily due to excess fructose, not sorbitol. This finding is crucial for understanding digestive issues in children after consuming apple juice.

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Area of Science:

  • Gastroenterology
  • Pediatrics
  • Human Nutrition

Background:

  • Apple juice consumption can lead to abdominal symptoms and diarrhea, particularly in children.
  • Fructose and sorbitol are suspected carbohydrate culprits in apple juice malabsorption.
  • Understanding the specific malabsorbed carbohydrate is key to managing digestive distress.

Purpose of the Study:

  • To investigate the malabsorption of carbohydrates in apple juice.
  • To determine whether fructose or sorbitol is responsible for malabsorption and associated symptoms.
  • To assess the role of fructose and sorbitol individually and in combination.

Main Methods:

  • Utilized the hydrogen breath test to measure carbohydrate absorption in 17 children and 12 adults.
  • Administered apple juice, fructose, sorbitol, and a fructose-sorbitol combination at specific dosages.

Related Experiment Videos

  • Analyzed peak breath hydrogen (H2) excretion levels to quantify malabsorption.

    • Main Results:

    • 65% of children and 33% of adults showed malabsorption of apple juice.
    • Fructose malabsorption was identified in 7 of 11 children, while sorbitol malabsorption was minimal.
    • Peak breath H2 levels were significantly higher after apple juice and fructose ingestion compared to the fructose-sorbitol combination.

    Conclusions:

    • Fructose, in excess of glucose, is the primary carbohydrate responsible for malabsorption and diarrhea after apple juice consumption.
    • Sorbitol does not appear to significantly contribute to or exacerbate malabsorption in this context.
    • This research clarifies the cause of digestive upset from apple juice, especially in toddlers.