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[The changes of intraocular pressure during sevoflurane anesthesia in children]
S Yoshitake1, K Sendaya, A Mizutani
1Department of Anesthesiology, Oita Medical University.
Insights
This study found no significant changes in intraocular pressure (IOP) during sevoflurane anesthesia in children. The optimal time for IOP measurement is 5-10 minutes post-intubation, with a normal range below 20 mmHg.
Area of Science:
- Anesthesiology
- Ophthalmology
- Pediatric Medicine
Background:
- Intraocular pressure (IOP) is a critical parameter in ophthalmic surgery and anesthesia.
- Understanding IOP fluctuations during pediatric anesthesia is essential for patient safety.
- Sevoflurane is a commonly used anesthetic agent in pediatric patients.
Purpose of the Study:
- To investigate the changes in intraocular pressure (IOP) during sevoflurane anesthesia in children.
- To determine the optimal timing for IOP measurement following intubation.
- To establish a normal IOP range during sevoflurane anesthesia in pediatric patients.
Main Methods:
- Prospective study involving 20 pediatric patients undergoing sevoflurane anesthesia.
- Intraocular pressure (IOP), mean blood pressure, and heart rate were measured at 7 time points.
- Measurements were taken post-induction, post-vecuronium, immediately post-intubation, and at 5, 10, 15, and 30 minutes post-intubation.
Main Results:
- No significant changes in IOP or hemodynamic parameters were observed during sevoflurane anesthesia.
- Peak IOP values were recorded at 5 minutes (19.2 mmHg) and 10 minutes (18.8 mmHg) post-intubation.
- The study suggests that 5 or 10 minutes post-intubation is the optimal time for IOP assessment.
Conclusions:
- Sevoflurane anesthesia appears to maintain stable intraocular pressure in children.
- A normal IOP range below 20 mmHg is suggested during sevoflurane anesthesia in this pediatric population.
- IOP measurement 5-10 minutes after intubation provides a reliable assessment during sevoflurane anesthesia.
Abstract:
We investigated the intraocular pressure (IOP) during sevoflurane anesthesia in 20 children. We measured IOP, mean blood pressure and heart rate at 7 points in each subject. IOP was measured first after induction, then after vecuronium administration, immediately after intubation, and 5, 10, 15, 30 min after intubation. There were no significant changes in IOP and hemodynamics during sevoflurane anesthesia. We consider that the optimal time for IOP measurement is 5 or 10 min after intubation and the normal range of IOP is within the mean +/- 2 standard deviation. The peak values of IOP were 19.2 and 18.8 mmHg at 5 and 10 min after intubation. The results suggest that normal range of IOP is below 20 mmHg during sevoflurane anesthesia in children.