Hypopigmented sarcoidosis in the negro. Report of eight cases with ultrastructural observations

The dermatological aspects of eight negro patients with hypopigmented sarcoid lesions are described. Light microscope histochemical studies in patients did not reveal the mechanism of the hypopigmentation. However, electronmicroscopy of lesions in two patients showed melanocytes undergoing changes resembling those observed in other acquired hypopigmentary conditions. It is suggested that in these disorders, melanocytes react morphologically in a similar non-specific manner, whatever the prime pathological process.