Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Morphological evidence for a cecocolonic junction in man and functional implications

M S Faussone-Pellegrini1, D Pantalone, C Cortesini

  • 1Department of Human Anatomy and Histology, University of Florence, Italy.

Acta Anatomica
|January 1, 1993
PubMed
Summary

Researchers identified a unique cecocolonic junction in humans, crucial for ileocecal valve function. This structure aids ileal flow, colonic movement, and valve control.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Facing Trauma and Surgical Emergency in Space: Hemorrhagic Shock.

Frontiers in bioengineering and biotechnology·2022
Same author

Changes of excitatory and inhibitory neurotransmitters in the colon of rats underwent to the wrap partial restraint stress.

Neurogastroenterology and motility·2016
Same author

Changes in nitrergic and tachykininergic pathways in rat proximal colon in response to chronic treatment with otilonium bromide.

Neurogastroenterology and motility·2015
Same author

Clinical-histological associations in gastroparesis: results from the Gastroparesis Clinical Research Consortium.

Neurogastroenterology and motility·2012
Same author

GLP-2 receptor expression in excitatory and inhibitory enteric neurons and its role in mouse duodenum contractility.

Neurogastroenterology and motility·2011
Same author

Epidemiology of dental professional liability.

Minerva stomatologica·2011

Area of Science:

  • Anatomy
  • Gastroenterology
  • Microscopy

Background:

  • The ileocecal valve regulates content passage between the small and large intestines.
  • Its precise anatomical structure and function in humans require further elucidation.

Purpose of the Study:

  • To investigate the anatomical features of the region surrounding the human ileocecal valve opening.
  • To characterize the cellular and tissue structures involved in ileocecal valve function.

Main Methods:

  • Light and electron microscopy were employed to study human tissue samples.
  • Detailed histological examination of the cecocolonic junction was performed.

Main Results:

  • A distinct cecocolonic junction was identified, formed by the colonic basal portion of the ileocecal valve.

Related Experiment Videos

  • This junction features a specific inner circular muscle layer with anastomosing cords, rich innervation, and elastic fibers.
  • Smooth muscle cells exhibit unique characteristics: wide sarcoplasmic cisternae, abundant glycogen, and numerous caveolae.

    • Conclusions:

    • The identified cecocolonic junction plays a role in accommodating ileal flow.
    • It is implicated in facilitating active colonic movements.
    • The structure is proposed to be responsible for the closing and opening mechanisms of the ileocecal valve.