Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Secondary thrombocytosis

A J Vora1, J S Lilleyman

  • 1Department of Paediatrics, University of Sheffield.

Archives of Disease in Childhood
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Secondary thrombocytosis, a high platelet count, is common in young infants, often following infection. This condition typically requires no treatment beyond addressing the underlying cause.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Observations on the measurement of zinc protoporphyrin in both whole blood and washed red cells in young children.

International journal of laboratory hematology·2018
Same author

Retrospective study of alemtuzumab vs ATG-based conditioning without irradiation for unrelated and matched sibling donor transplants in acquired severe aplastic anemia: a study from the British Society for Blood and Marrow Transplantation.

Bone marrow transplantation·2013
Same author

Reference intervals for red cell variables and platelet counts in infants at 2, 5 and 13 months of age: a cohort study.

Journal of clinical pathology·2013
Same author

BTG1 deletions do not predict outcome in Down syndrome acute lymphoblastic leukemia.

Leukemia·2012
Same author

Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations.

Leukemia·2012
Same author

Meta-analysis of randomised trials comparing thiopurines in childhood acute lymphoblastic leukaemia.

Leukemia·2011
Same journal

Artificial intelligence for child health: current capabilities and the next frontier.

Archives of disease in childhood·2026
Same journal

Troubled origins and lasting impact of the first insulin injection.

Archives of disease in childhood·2026
Same journal

Paediatric readiness assessment tools in emergency care: a scoping review.

Archives of disease in childhood·2026
Same journal

Building a paediatric workforce to deliver the NHS prevention agenda: time for paediatric public health medicine?

Archives of disease in childhood·2026
Same journal

Impact of antenatal biological response modifying drugs on infant infection risk and vaccination rates: a national cohort study.

Archives of disease in childhood·2026
Same journal

Draft charter for asthma in children and young people, inspired by Martha's rule.

Archives of disease in childhood·2026
See all related articles

Area of Science:

  • Pediatric Hematology
  • Clinical Pathology

Background:

  • Secondary thrombocytosis, defined as elevated platelet counts (> 800 x 10(9)/l), is a recognized clinical finding.
  • Understanding its incidence and etiology in pediatric populations is crucial for appropriate patient management.

Purpose of the Study:

  • To determine the incidence and common causes of secondary thrombocytosis in children.
  • To analyze data from a prospective study alongside previous research for a comprehensive overview.

Main Methods:

  • A 12-month observational study of pediatric patients with platelet counts exceeding twice the upper normal limit.
  • Analysis of data from 36 new cases, combined with data from two prior studies, totaling 139 children.

Main Results:

Related Experiment Videos

  • The incidence of secondary thrombocytosis was 0.5% (36/7916 children), with a median age of 13 months.
  • Infections were the most frequent cause (53%), followed by tissue damage (20%) and malignancy (11%).
  • Other causes included chemotherapy recovery, post-operative states, and iron deficiency.

    • Conclusions:

    • Secondary thrombocytosis is not rare in children, particularly in young infants post-infection.
    • It can also result from various conditions like myelosuppression rebound, iron deficiency, or acute phase response.
    • The condition is generally clinically insignificant and does not require specific treatment.