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Acute generalized exanthematous pustulosis due to doxycycline
Summary
Drug hypersensitivity can cause sterile epidermal neutrophilic pustulation. A case study confirmed doxycycline as the cause of generalized pustulosis in a patient, with lymphocyte testing validating the drug-induced reaction.
Area of Science:
- Dermatology
- Pharmacology
- Immunology
Background:
- Sterile epidermal neutrophilic pustulation is a dermatological sign associated with various conditions.
- Drug hypersensitivity is an infrequent but recognized cause of generalized pustulosis.
- Differential diagnosis for generalized pustulosis includes several dermatoses.