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Topical retinoids. Their uses in dermatology
M Verschoore1, M Bouclier, J Czernielewski
1Clinical Research Department, Valbonne, France.
Dermatologic Clinics
|January 1, 1993
Summary
New retinoids, like adapalene, offer improved treatments for skin conditions with less irritation. These promising compounds are undergoing clinical trials for future dermatologic use.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Retinoids are established treatments for dermatologic disorders.
- Retinoids also play a role in preventing new lesion formation.
Purpose of the Study:
- To introduce novel retinoids with enhanced efficacy and reduced irritation.
- To evaluate the clinical potential of new retinoid molecules.
Main Methods:
- Synthesis of new retinoid compounds.
- Clinical investigation of these novel molecules.
Main Results:
- Preliminary clinical data show encouraging outcomes.
- New retinoids demonstrate potential for comparable or superior efficacy.
- Reduced skin irritation observed with new retinoid formulations.
Conclusions:
- New retinoids, including adapalene, represent a significant advancement in dermatologic therapy.
- Further clinical investigation is ongoing for these promising agents.
- An expanded selection of topical retinoids is anticipated in the near future.