Related Experiment Video
Updated: Aug 11, 2026
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Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
Published on: December 23, 2022
[Closure of a persistent ductus arteriosus Botallo without thoracotomy]
L Belau1, L Grävinghoff, E W Keck
1Kardiologische Abteilung, Universitäts-Krankenhaus Eppendorf, Hamburg.
Deutsche Medizinische Wochenschrift (1946)
|February 12, 1993
Summary
The Rashkind occlusion system effectively closed persisting ductus arteriosus (PDA) in most patients. This minimally invasive procedure is suitable for patients over 5 kg with PDA diameters less than 10 mm.
Area of Science:
- Cardiovascular Medicine
- Pediatric Cardiology
- Interventional Cardiology
Context:
- A persisting ductus arteriosus (PDA) is a congenital heart defect requiring intervention.
- Traditional closure methods can be invasive.
- The Rashkind occlusion system offers a less invasive alternative.
Purpose:
- To evaluate the efficacy and safety of the Rashkind occlusion system for closing PDA.
- To assess outcomes in both pediatric and adult patients.
Summary:
- The Rashkind occlusion system was used to close PDA in 15 patients (12 children, 3 adults).
- The device, a double umbrella, is implanted via a catheter, promoting closure through thrombosis and epithelialization.
- Mean PDA diameter was 2.4 mm (range 1.4-5.3 mm).
- Complete occlusion was achieved in 8 patients; residual shunts in 7.
- One adult with a residual shunt required surgical closure due to hemolysis.
Impact:
- The Rashkind method is a sparing and minimally invasive procedure for PDA closure.
- It is indicated for patients weighing over 5 kg with PDA diameters less than 10 mm.
- The study demonstrates a favorable safety profile with no procedural complications or embolization.
