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Related Experiment Videos

Dermatitis in treated maple syrup urine disease

S E Koch1, S Packman, T K Koch

  • 1Department of Dermatology, University of California, San Francisco.

Journal of the American Academy of Dermatology
|February 1, 1993
PubMed
Summary

Maple syrup urine disease (MSUD) can cause skin issues. Supplementing isoleucine and leucine rapidly resolved eruptive dermatitis in children with MSUD during protein restriction.

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Area of Science:

  • Biochemistry
  • Dermatology
  • Genetics

Background:

  • Maple syrup urine disease (MSUD) is a rare inherited metabolic disorder.
  • MSUD is characterized by the inability to metabolize branched-chain amino acids (BCAAs), leading to their accumulation in the body.
  • Protein restriction is a common management strategy for MSUD.