Multiple pregnancies as a result of IVF and ET in a program without cryopreservation possibility

Of the 71 clinical pregnancies achieved in the IVF and ET program at the Institute for the Care of Mother and Child between January 1989 and June 1992 22 were multiple (30.9%). In seven cases (31.3%) spontaneous reduction occurred. A total of six patients underwent a multi-fetal pregnancy reduction. Close monitoring of ovarian response, limitation of the number of transferred embryos, selection of the most viable embryos using cocultivation systems and embryo freezing should be used to avoid the higher order multiple pregnancies after IVF ET.