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Updated: Aug 10, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
Intussusception in preterm infants
K J Price1, N R Roberton, R G Pearse
1Jessop Hospital for Women, Sheffield.
Insights
Intussusception in preterm infants can mimic necrotising enterocolitis. Early consideration of intussusception is crucial for timely diagnosis and treatment in neonates with these symptoms.
Area of Science:
- Neonatal surgery
- Pediatric gastroenterology
Background:
- Intussusception is a surgical emergency where one part of the intestine slides into another.
- Necrotising enterocolitis (NEC) is a serious gastrointestinal condition affecting premature infants.
Observation:
- Two preterm infants (26 and 30 weeks gestation) presented with abdominal distension, feeding intolerance, and rectal bleeding.
- Initial diagnosis was necrotising enterocolitis, leading to delayed diagnosis of intussusception.
Findings:
- Presenting signs and symptoms of neonatal intussusception can overlap significantly with those of necrotising enterocolitis.
- Medical management for suspected NEC can delay the diagnosis of intussusception.
Implications:
- Clinicians should consider intussusception in the differential diagnosis of preterm infants presenting with symptoms suggestive of necrotising enterocolitis.
- Prompt recognition and diagnosis of intussusception are vital to prevent complications in preterm neonates.
Abstract:
Two cases of intussusception in infants born at 26 and 30 weeks' gestation are described. The two infants presented in the neonatal period with abdominal distension, intolerance of feeds, and rectal bleeding. An initial diagnosis of necrotising enterocolitis was made and the infants were treated medically. This led to a delay in the diagnosis of the intussusception. Published work on neonatal intussusception is reviewed and attention is drawn to the fact that the presenting signs and symptoms can be similar to those of necrotising enterocolitis. A diagnosis of intussusception should therefore be considered in any preterm infant with suspected necrotising enterocolitis.
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