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Measles control in developing and developed countries: the case for a two-dose policy
T H Tulchinsky1, G M Ginsberg, Y Abed
1Preventive Health Services, Ministry of Health, Jerusalem, Israel.
Bulletin of the World Health Organization
|January 1, 1993
Summary
A two-dose measles vaccination program significantly improves individual protection and herd immunity, contributing to disease control and elimination. This strategy is cost-beneficial for both developed and developing nations.
Area of Science:
- Immunology
- Public Health
- Vaccinology
Background:
- Single-dose measles vaccination (Schwarz strain) has not eradicated measles in developed countries.
- Measles continues to cause significant mortality and disability in developing nations despite increased immunization efforts.
Purpose of the Study:
- To evaluate the effectiveness and cost-benefit of a two-dose measles vaccination program for disease control and elimination.
- To advocate for the adoption of a two-dose schedule as essential preventive healthcare.
Main Methods:
- Review of empirical evidence from various countries on measles vaccination programs.
- Cost-benefit analysis of single-dose versus two-dose vaccination schedules.
Main Results:
- A two-dose measles vaccination program enhances individual immunity and herd immunity, aiding disease control.
- The two-dose schedule is supported by cost-benefit analyses, showing savings in healthcare and societal costs.
Conclusions:
- A two-dose measles vaccination program is crucial for measles control and elimination in both developing and developed countries.
- Implementing a two-dose schedule is a vital component of preventive healthcare for the 1990s.