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Related Experiment Videos

Physically induced pemphigus after cosmetic procedures

R P Kaplan1, S P Detwiler, H W Saperstein

  • 1Division of Dermatology, University of California, Los Angeles School of Medicine.

International Journal of Dermatology
|February 1, 1993
PubMed
Summary
This summary is machine-generated.

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Cosmetic procedures may trigger pemphigus, an autoimmune skin condition. This study highlights two cases where pemphigus lesions appeared after cosmetic surgery and chemical peels, suggesting a link between trauma and disease onset.

Area of Science:

  • Dermatology
  • Autoimmune diseases

Background:

  • Pemphigus is an autoimmune blistering disease caused by antibodies targeting epidermal antigens.
  • Characterized by acantholysis, leading to skin lesions.

Observation:

  • Two cases of pemphigus lesions developing in areas of cosmetic procedure trauma are presented.
  • One patient experienced pemphigus in surgical scars post-mammoplasty and facelift.
  • Another patient had a pemphigus outbreak after a chemical peel.

Findings:

  • Cosmetic procedures, including surgery and chemical peels, may act as triggers for pemphigus.
  • Lesions localized to traumatized areas suggest a Koebner phenomenon-like response in pemphigus.

Implications:

  • Cosmetic procedures should be considered potential initiators of pemphigus.

Related Experiment Videos

  • New-onset pemphigus in surgical sites requires differentiation from wound healing complications.