Related Experiment Videos
Trisomy 21 presented as a transient unilateral pleural effusion at 18 weeks' gestation
D M Sherer1, J S Abramowicz, S R Sanko
1Department of Obstetrics and Gynecology, Strong Memorial Hospital, University of Rochester School of Medicine and Dentistry, NY 14642-8668.
American Journal of Perinatology
|January 1, 1993
Summary
A rare case of fetal pleural effusion resolved spontaneously. Chromosomal analysis is suggested for similar cases with resolved fluid accumulation.
Area of Science:
- Perinatology
- Fetal Medicine
- Genetics
Background:
- Fetal pleural effusion, an accumulation of fluid in the pleural space, can be a serious complication during pregnancy.
- While often associated with chromosomal abnormalities or hydrops fetalis, spontaneous resolution is uncommon.
Observation:
- A unilateral fetal pleural effusion was identified at 18 weeks' gestation.
- The effusion demonstrated complete spontaneous resolution by 19 weeks' gestation.
Findings:
- Karyotype analysis via amniocentesis revealed trisomy 21 (Down syndrome).
- This case highlights a rare instance of spontaneous resolution of fetal pleural effusion in the context of a chromosomal abnormality.
Implications:
- Consider chromosomal analysis in pregnancies with spontaneous resolution of fetal effusions.
- Early identification and genetic assessment can inform management and counseling for fetal conditions.