Related Experiment Video
Updated: Aug 3, 2026

Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Constitutive heterochromatin polymorphisms in children with acute lymphoblastic leukemia
A Tsezou1, S Kitsiou-Tzeli, H Kosmidis
12nd Department of Pediatrics, University of Athens, P & A Kyriakou Children's Hospital, Greece.
Abstract:
The C-band heterochromatin polymorphisms of chromosomes 1, 9, and 16 were studied on peripheral lymphocytes of 67 children with acute lymphoblastic leukemia (ALL) and 50 control individuals. A statistically significant difference between patients and controls was found for large heterochromatin regions (level 3) of chromosomes 1 and 9 (P < 0.001) and for small heterochromatin regions (level 1) of chromosome 16 (P < 0.001). The patients also showed a significant increase in chromosomes 1 and 9 heteromorphism with respect to controls (P < 0.001).
More Related Videos
Related Concept Videos
Histone Variants at the Centromere
Inheritance of Chromatin Structures
Euchromatin
Euchromatin is the less dense region of the chromatin and stains lighter. Euchromatin contains histone H3 extensively...
Non-LTR Retrotransposons
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Heterochromatin
Constitutive heterochromatin: It is a highly compact region of chromatin that is mostly concentrated in the centromere and telomere. Unlike euchromatin, the amino acid at 9th...

