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Related Experiment Videos

Gender, depression, and ankylosing spondylitis

J H Barlow, S J Macey, G R Struthers

    Arthritis Care and Research : the Official Journal of the Arthritis Health Professions Association
    |March 1, 1993
    PubMed
    Summary

    Depression affects one-third of ankylosing spondylitis patients, with women experiencing more symptoms than men. Pain significantly impacts depression in women, challenging typical patient stereotypes.

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    Area of Science:

    • Rheumatology
    • Psychiatry
    • Epidemiology

    Background:

    • Depression is a known complication of rheumatoid arthritis.
    • Limited research exists on depressive symptoms in other arthritic conditions, such as ankylosing spondylitis (AS).
    • This study addresses the gap in understanding AS psychosocial aspects.

    Purpose of the Study:

    • To determine the prevalence of depressive symptoms in ankylosing spondylitis (AS) patients.
    • To identify factors influencing depressive symptoms in AS.
    • To investigate gender differences in depression and its determinants within the AS population.

    Main Methods:

    • Cross-sectional study design.
    • Inclusion of patients diagnosed with ankylosing spondylitis.
    • Assessment of depressive symptoms and potential determinants, including pain.
    • Analysis of gender-specific differences.

    Main Results:

    • Approximately 33% of ankylosing spondylitis patients reported high levels of depressive symptoms.
    • Women with AS reported significantly higher depression scores than men.
    • Pain was a primary determinant of depression for women, but less so for men.
    • Findings do not support the stereotype of AS patients being less depressed than those with other arthritis forms.

    Conclusions:

    • Depressive symptoms are prevalent in ankylosing spondylitis (AS) patients.
    • Gender influences both the experience and determinants of depression in AS.
    • Targeted interventions for depression in AS should consider gender-specific factors, particularly pain management for women.

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