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Umbilical cord clamping and preterm infants: a randomised trial
S Kinmond1, T C Aitchison, B M Holland
1Queen Mother's Hospital, Department of Child Health, University of Glasgow.
BMJ (Clinical Research Ed.)
|January 16, 1993
Summary
Regulated umbilical cord clamping in preterm infants improved packed cell volume and reduced the need for red blood cell transfusions. This method also decreased respiratory impairment, offering clinical and economic benefits.
Area of Science:
- Neonatal Medicine
- Perinatal Care
- Obstetrics
Background:
- Preterm infants often experience complications related to placental transfusion.
- Delayed umbilical cord clamping is a potential intervention to improve neonatal outcomes.
Purpose of the Study:
- To investigate the clinical effects of regulating umbilical cord clamping in preterm infants.
Main Methods:
- Prospective randomized study involving 36 preterm infants (27-32 weeks gestation).
- Intervention: delayed cord clamping (30 seconds) vs. conventional management.
- Outcome measures included packed cell volume, bilirubin levels, transfusion needs, and respiratory impairment.
Main Results:
- Regulated clamping group showed higher initial packed cell volume (0.564 vs. 0.509) and lower transfusion requirements (0 vs. 23 ml/kg).
- Significant improvements in arterial-alveolar oxygen tension ratio and reduced duration of oxygen dependence (3 vs. 10 days) were observed.
- Respiratory impairment was significantly reduced in the regulated group.
Conclusions:
- Regulating umbilical cord clamping in preterm deliveries yields significant clinical benefits.
- This intervention demonstrates potential economic advantages in neonatal care.