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Intrathecal baclofen in severe spasticity

B N McLean1

  • 1Royal Cornwall Hospital, Treliske, Truro.

British Journal of Hospital Medicine
|February 2, 1993
PubMed
Summary

Intrathecal baclofen pump therapy offers improved control for severe spasticity in patients resistant to oral medications. This review covers the technique, indications, outcomes, and complications of this advanced treatment.

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Area of Science:

  • Neurology
  • Neurosurgery
  • Pharmacology

Background:

  • Severe spasticity significantly impacts patient quality of life and functional independence.
  • Oral medications are often insufficient for managing severe spasticity, leading to treatment resistance.
  • Intrathecal baclofen administration offers a targeted approach to spasticity management.

Purpose of the Study:

  • To review the rationale and clinical indications for intrathecal baclofen pump therapy.
  • To evaluate the outcomes and efficacy of this treatment modality.
  • To discuss the complications associated with intrathecal baclofen administration.

Main Methods:

  • Review of existing literature on intrathecal baclofen pump therapy.
  • Analysis of clinical data regarding patient selection and treatment protocols.
  • Examination of reported outcomes, including efficacy and adverse events.

Main Results:

  • Intrathecal baclofen pump therapy provides effective control of severe spasticity in patients unresponsive to oral treatments.
  • The technique is indicated for various conditions causing severe spasticity.
  • Complications, though possible, are manageable with appropriate monitoring and intervention.

Conclusions:

  • Intrathecal baclofen pump therapy represents a significant advancement in managing severe spasticity.
  • Careful patient selection and management are crucial for optimizing outcomes.
  • This therapeutic approach offers substantial benefits for patients with refractory spasticity.

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