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Development of the diffuse endocrine system in the chicken proventriculus
1Department of Cytology and Histology, University of Navarra, Pamplona, Spain.
Cell and Tissue Research
|January 1, 1993
Summary
Chicken proventriculus endocrine cell development was studied. Morphologically distinct cells appeared by embryonic day 5, with specific substance immunoreactivities emerging from day 14 onwards.
Area of Science:
- Developmental biology
- Gastrointestinal physiology
- Cell biology
Background:
- The chicken proventriculus is a key component of the avian digestive system.
- Understanding the development of its endocrine cells is crucial for comprehending digestive regulation.
Purpose of the Study:
- To investigate the developmental timeline of endocrine cells in the chicken proventriculus.
- To characterize the morphological and immunocytochemical changes during their differentiation.
Main Methods:
- Light and electron microscopy were employed.
- Silver impregnation and immunocytochemical techniques were utilized.
- Embryonic and post-hatch tissues were analyzed at various developmental stages.
Main Results:
- Morphologically identifiable endocrine cells emerged by embryonic day 5.
- Open-type endocrine cells decreased while closed-type cells increased post-day 13.
- Immunoreactivity to serotonin, avian pancreatic polypeptide, glucagon, somatostatin, bombesin, neurotensin, and met-enkephalin appeared sequentially from day 14 to day 21.
Conclusions:
- Chicken proventriculus endocrine cells differentiate progressively throughout embryonic development.
- The sequential appearance of immunoreactivities suggests a specific differentiation pathway.
- These findings provide insights into the development of gastrointestinal endocrine signaling in birds.