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Immune-complex-trapping cells in the spleen of the oriental fire-bellied toad, Bombina orientalis

J Dulak1, J Bauer, E A Döpp

  • 1Department of Histology, Medical Faculty, Free University, Amsterdam, The Netherlands.

Cell and Tissue Research
|January 1, 1993
PubMed

The spleen of the oriental fire-bellied toad, Bombina orientalis, consists of well-developed white pulp, separated from the lymphocytic marginal zone by the connective tissue boundary layer. Injection of peroxidase-conjugated rabbit anti-peroxidase revealed that these immune complexes were localized on the surface of acid-phosphatase-positive and non-specific-esterase-positive cells in the white pulp. The majority of immune-complex-trapping cells were present around the blood vessels. Cell processes of some of these cells penetrated into the wall of blood vessels. The significance of the present findings is discussed with respect to the evolution of immune-complex-trapping cells in the spleen.

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