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A long-term ventricular assist system

W S Pierce1, A J Snyder, G Rosenberg

  • 1Department of Surgery, College of Medicine, Pennsylvania State University, Hershey 17033.

The Journal of Thoracic and Cardiovascular Surgery
|March 1, 1993
PubMed
Summary
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This study developed a tether-free, implantable electric blood pump for circulatory support. Animal trials showed promising results, suggesting potential for a reliable 2-year assist pump for clinical use.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Implantable Pumps

Background:

  • Circulatory support is crucial for patients with heart failure.
  • Existing devices often require external connections, posing risks.
  • Tether-free solutions are needed for improved patient mobility and reduced complications.

Purpose of the Study:

  • To develop and evaluate an implantable, electrically powered, tether-free blood pump.
  • To assess the feasibility and performance of the device in animal models.
  • To determine the potential for long-term clinical application.

Main Methods:

  • Development of a sealed blood pump with a polyurethane sac and polysulfone case.
  • Utilized Björk-Shiley Monostrut valves for unidirectional flow.

Related Experiment Videos

  • Employed a brushless DC motor, pusher plate actuation, and inductive coupling for power transmission.
  • Tested the device in 26 animals for circulatory support.

    • Main Results:

    • The pump achieved a flow rate of 8.5 L/min at physiologic pressures.
    • Circulatory support was provided to animals for over 1 week, averaging 62 days (longest: 8 months).
    • Pump-related issues occurred in 18 animals; biologically related issues in 8.

    Conclusions:

    • The developed tether-free implantable blood pump shows encouraging results for circulatory support.
    • Further refinement may lead to a reliable 2-year assist pump with significant clinical potential.
    • This technology could offer a viable alternative to current circulatory support systems.