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Acute right ventricular heart failure in a patient with renal cell carcinoma after interferon therapy
C Kramers1, P H de Mulder, J D Barth
1Department of Medical Oncology, University Hospital Nijmegen, Netherlands.
Abstract:
In a patient with diffuse pulmonary metastases of a renal cell carcinoma the development of severe pulmonary hypertension is described after reaching a complete remission during treatment with r-IFN-alpha 2c and rIFN-gamma. Rechallenge with interferon after the discovery of recurrent disease did not lead to deterioration of the cardiopulmonary condition. Possible causative mechanisms are discussed.
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