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Auditory brainstem potentials in uraemia
1Clinic of Otorhinolaryngology, Semmelweis University, Budapest, Hungary.
Summary
Hemodialysis patients show impaired auditory pathways. Evoked response audiometry revealed longer wave latencies, suggesting central auditory dysfunction in renal patients.
Area of Science:
- Nephrology
- Audiology
- Neuroscience
Background:
- Chronic kidney disease requiring hemodialysis can affect neurological function.
- Auditory pathway integrity is crucial for communication and quality of life.
Purpose of the Study:
- To evaluate the auditory pathway's viability in patients undergoing hemodialysis.
- To identify potential auditory dysfunction in this patient population.
Main Methods:
- Evoked response audiometry (ERA) was employed.
- Latency of auditory brainstem response waves (III, V) and I-V interpeak latencies were measured.
- Hemodialysis patients were compared to a control group.
Main Results:
- Significantly longer latencies for waves III, V, and I-V interpeak were observed in hemodialysis patients.
- 8 out of 13 patients exceeded the upper limit for I-V interpeak latency (4.38 ms).
Conclusions:
- Hemodialysis is associated with central auditory dysfunction.
- Potential causes include metastatic calcifications, disequilibrium syndrome, and toxic metabolic substances.
- The contribution of each factor may differ across hemodialysis centers.