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Auditory brainstem potentials in uraemia

M Küstel1, B Büki, J Gyimesi

  • 1Clinic of Otorhinolaryngology, Semmelweis University, Budapest, Hungary.

ORL; Journal for Oto-Rhino-Laryngology and Its Related Specialties
|March 1, 1993
PubMed
Summary
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Hemodialysis patients show impaired auditory pathways. Evoked response audiometry revealed longer wave latencies, suggesting central auditory dysfunction in renal patients.

Area of Science:

  • Nephrology
  • Audiology
  • Neuroscience

Background:

  • Chronic kidney disease requiring hemodialysis can affect neurological function.
  • Auditory pathway integrity is crucial for communication and quality of life.

Purpose of the Study:

  • To evaluate the auditory pathway's viability in patients undergoing hemodialysis.
  • To identify potential auditory dysfunction in this patient population.

Main Methods:

  • Evoked response audiometry (ERA) was employed.
  • Latency of auditory brainstem response waves (III, V) and I-V interpeak latencies were measured.
  • Hemodialysis patients were compared to a control group.

Main Results:

  • Significantly longer latencies for waves III, V, and I-V interpeak were observed in hemodialysis patients.

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  • 8 out of 13 patients exceeded the upper limit for I-V interpeak latency (4.38 ms).

    • Conclusions:

    • Hemodialysis is associated with central auditory dysfunction.
    • Potential causes include metastatic calcifications, disequilibrium syndrome, and toxic metabolic substances.
    • The contribution of each factor may differ across hemodialysis centers.