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Updated: Aug 13, 2026

Facilitating Drug Discovery: An Automated High-content Inflammation Assay in Zebrafish
Published on: July 16, 2012
Nonsteroidal anti-inflammatory drugs. Tailoring therapy to achieve results and avoid toxicity
P Amadio1, D M Cummings, P Amadio
1Jefferson Medical College, Thomas Jefferson University, Department of Family Medicine, Philadelphia, PA 19107.
Abstract:
When used appropriately, non-steroidal anti-inflammatory drugs (NSAIDs) are safe and effective for treating pain and inflammation. NSAIDs that block both the lipoxygenase and cyclooxygenase pathways may be advantageous in some patients. New classes of NSAIDs that may have a more favorable safety profile than older agents may improve patient outcome. However, all patients receiving NSAIDs, especially the elderly, should be carefully monitored for possible drug-related complications.
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