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Interferon-associated retinopathy
D R Guyer1, J Tiedeman, L A Yannuzzi
1Retinal Research Laboratory, Manhattan Eye, Ear, and Throat Hospital, New York, NY 10021.
Archives of Ophthalmology (Chicago, Ill. : 1960)
|March 1, 1993
Summary
Interferon alfa (IFN-α) therapy can cause retinal ischemia, including capillary closure and vision loss. Monitoring patients on IFN-α is crucial for early detection and potential reversal of these sight-threatening complications.
Area of Science:
- Ophthalmology
- Oncology
- Immunology
Background:
- Interferon alfa (IFN-α) is a cytokine used to treat systemic disorders.
- IFN-α has been investigated for treating choroidal neovascularization.
- Retinal vascular complications are a potential side effect of systemic therapies.