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Chemonucleolysis. Personal history, trials, and tribulations
1Department of Orthopaedic Surgery, Northwestern University Medical School, Lake Wales, Florida.
Clinical Orthopaedics and Related Research
|February 1, 1993
Summary
Chemonucleolysis, a controversial procedure, is reviewed from 1963 to present. Properly selected patients show chemonucleolysis is as effective and safe as laminectomy.
Area of Science:
- Spinal Surgery
- Interventional Pain Management
Background:
- Chemonucleolysis involves injecting enzymes to dissolve disc material.
- Its history is marked by controversy and evolving techniques.
Purpose of the Study:
- To review the historical development and controversial aspects of chemonucleolysis.
- To evaluate its current efficacy and safety compared to laminectomy.
Main Methods:
- Literature review of studies from 1963 to the present.
- Analysis of historical data and recent clinical findings.
Main Results:
- Chemonucleolysis has a complex and debated history.
- Recent evidence supports its effectiveness and safety in select patient populations.
Conclusions:
- Chemonucleolysis is a viable alternative to laminectomy for specific patients.
- Proper patient selection is crucial for successful chemonucleolysis outcomes.