Lipoprotein metabolism in the frog Rana esculenta

1. The isoprenoid metabolism of the green frog has been studied, taking into consideration the transport and uptake mechanisms of plasma lipoproteins. 2. The lipoprotein complexes separated on KBr gradient showed six discrete peaks in both sexes. 3. The mechanisms of cellular uptake have been studied by immunological procedures. A molecule homologous to rat LDL receptor, and sharing its ability to bind only specific lipoproteins, has been shown. 4. Homology at mRNA level has also been demonstrated by Northern blot analysis and two different messengers have been shown in both male and female frog.