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Assignment of the mouse tartrate-resistant acid phosphatase gene (Acp5) to chromosome 9
R Grimes1, S V Reddy, R J Leach
1Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio 78284.
Genomics
|February 1, 1993
Abstract:
Tartrate-resistant acid phosphatase is a marker enzyme for osteoclasts, the multinucleated cell responsible for bone resorption. Interspecific somatic whole cell hybrids and karyotypically simple microcell hybrids were used to map the gene encoding tartrate-resistant acid phosphatase (Acp5) to mouse Chromosome 9. Acp5 is therefore a member of a syntenic family of genes that map to human chromosome 19p13.1-p13.3 and mouse Chromosome 9.