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Measuring vision with temporally modulated stripes in infants and children with ROP
O Katsumi1, J K Kronheim, M C Mehta
1Clinical Research Unit, Schepens Eye Research Institute, Boston, MA 02114.
Insights
Preferential looking (PL) acuity testing reveals that temporally modulated stripes better assess vision in retinopathy of prematurity (ROP) patients with visual impairment. This method is crucial for evaluating severely visually impaired individuals.
Area of Science:
- Ophthalmology
- Pediatric Medicine
- Vision Science
Background:
- Retinopathy of prematurity (ROP) is a leading cause of childhood blindness.
- Accurate visual acuity assessment in infants and young children with ROP is challenging.
- Preferential looking (PL) is a psychophysical method used to estimate visual acuity.
Purpose of the Study:
- To compare preferential looking (PL) visual acuities using stationary and temporally modulated stripe patterns.
- To determine if temporal modulation improves acuity measurements in patients with retinopathy of prematurity (ROP).
Main Methods:
- PL acuities were measured in 134 patients (4 months to 13 years) with varying stages of ROP.
- Patients were categorized into six subgroups based on PL acuity with stationary stripes.
- Acuities were assessed using both stationary and temporally modulated stripe patterns.
Main Results:
- No significant difference was observed in patients with visual acuity (VA) better than 20/200.
- Temporally modulated stripes yielded significantly better acuities in patients with VA worse than 20/200.
- The difference in acuity, measured in octaves, increased with greater visual impairment, reaching 1.69 octaves in the most impaired group.
- Patients with no measurable stationary vision could detect temporally modulated stripes.
Conclusions:
- The discrepancy between temporally modulated and stationary stripe PL acuity increases with the severity of visual impairment in ROP.
- PL acuity testing with temporally modulated stripes is a valuable tool for assessing severely visually impaired individuals with ROP.
- This method enhances the evaluation of visual function in complex pediatric eye conditions.
Purpose:
To determine differences in preferential looking (PL) acuities using stationary and temporally modulated stripe patterns in patients with various stages of retinopathy of prematurity (ROP).
Methods:
We measured the PL acuities of 134 patients (ages 4 mo to 13 yr) with various stages of ROP. Patients were divided into six subgroups according to PL vision measured with stationary stripes: (1) equal to or better than 20/200 (n = 24); (2) worse than 20/200 to 20/400 (n = 10); (3) worse than 20/400 to 20/800 (n = 15); (4) worse than 20/800 to 20/1600 (n = 13); (5) worse than 20/1600 to 20/6400 (n = 26); and (6) worse than 20/6400 (n = 46; no stationary vision).
Results:
In the group with PL acuity equal to or better than 20/200, no difference in vision was apparent between the two methods. In patients with acuities worse than 20/200 to 20/400, the temporally modulated PL acuities were 0.23 octave better than the PL acuities measured with the stationary stripes. The difference increased to 0.86 and 1.12 octaves in the groups with visual acuities worse than 20/400 to 20/800 and worse than 20/800 to 20/1600, respectively. The difference in the group with PL acuities worse than 20/1600 to 20/6400 was 1.69 octaves. The 46 patients with no stationary vision detected only the temporally modulated stripes.
Conclusions:
The results suggest that the PL acuity difference between the temporally modulated and stationary stripes increases with visual impairment. Measuring PL acuity with temporally modulated stripes is an important addition to the evaluation of severely visually impaired subjects.