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Updated: Aug 15, 2026

Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
Published on: July 23, 2016
Unilateral gonadectomy does not alter contralateral intraocular pressure in rabbit eyes
Abstract:
The purpose of this study was to determine whether unilateral gonadectomy caused any change in intraocular pressure. Repeated measurements in 22 male and nine female rabbits after unilateral gonadectomy were made by three different methods of determining intraocular pressure. We were unable to find a decrease in intraocular pressure on the side opposite to the side of the removed gonad, as had been previously reported. Neither were any ipsilateral changes observed. A calibration curve (rabbit) for the applanation pneumatonograph is also presented.
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