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Related Experiment Videos

A 14/20 chromosome translocationp in Simmental cattle

R A McFeely1, L R Klunder, J A Reed

  • 1Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.

Journal of the American Veterinary Medical Association
|February 15, 1993
PubMed
Summary

A chromosomal abnormality, the 14/20 translocation, was found in Simmental cattle herds in the US. Caution is advised for breeding stock due to potential fertility issues and widespread dissemination via artificial insemination.

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Area of Science:

  • Veterinary Genetics
  • Animal Breeding
  • Cytogenetics

Background:

  • A specific chromosomal abnormality, the 14/20 translocation, has been identified in Simmental cattle.
  • The translocation was traced to a common sire whose semen was widely used for artificial insemination.

Purpose of the Study:

  • To report the identification of the 14/20 translocation in US Simmental cattle.
  • To highlight the potential implications for cattle breeding and fertility.

Main Methods:

  • Cytogenetic analysis to identify the 14/20 translocation.
  • Pedigree analysis to trace the origin of the translocation.

Main Results:

  • The 14/20 translocation was confirmed in two Simmental cattle herds.

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  • A single bull, used extensively for artificial insemination, was identified as the carrier sire.
  • A substantial portion of the US Simmental population may potentially carry this translocation.

    • Conclusions:

    • The widespread use of the carrier sire necessitates caution in selecting breeding stock.
    • Further research is needed to determine the exact impact of the 14/20 translocation on fertility.
    • Preventing the dissemination of this translocation is crucial for maintaining herd fertility.