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Late infection after total hip replacement

E M Downes

    The Journal of Bone and Joint Surgery. British Volume
    |February 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Deep hip infections can occur years after McKee-Farrar prosthesis replacement. These infections often originate from a distant source, not the surgical site itself.

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    Area of Science:

    • Orthopedic surgery
    • Infectious disease
    • Biomaterials science

    Background:

    • Total hip replacement (THR) using McKee-Farrar prostheses is a common procedure.
    • Deep prosthetic joint infections (PJIs) are a serious complication following THR.
    • The timing and origin of PJIs can be variable and challenging to diagnose.

    Observation:

    • A case series of four patients experiencing deep hip infections after McKee-Farrar THR is presented.
    • Infections manifested an average of 3.5 years post-implantation.
    • Multiple prosthetic components were affected across the six hips.

    Findings:

    • Strong evidence linked the deep hip infections to a distant infectious focus in all reported cases.
    • The distant source suggests hematogenous seeding as a potential mechanism.

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  • No intraoperative contamination was implied as the primary cause.

    • Implications:

    • This highlights the importance of considering non-surgical site origins for late-onset PJIs.
    • Diagnostic protocols for late PJIs should include screening for distant infections.
    • Understanding infection pathways can inform prevention and treatment strategies for prosthetic joint infections.