Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pilomatrix carcinoma

P Sau1, G P Lupton, J H Graham

  • 1Department of Dermatology, Walter Reed Army Medical Center, Washington, DC 20307-5001.

Cancer
|April 15, 1993
PubMed
Summary
This summary is machine-generated.

Pilomatrix carcinoma, a rare malignant skin cancer, often recurs locally, particularly when incompletely removed. Aggressive features and deep infiltration correlate with poorer outcomes, necessitating wide surgical excision.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

WATER RELATIONS OF MYCORRHIZAL AND PHOSPHORUS-FERTILIZED NON-MYCORRHIZAL CITRUS UNDER DROUGHT STRESS.

The New phytologist·2021
Same author

The Influence of Spray Adjuvants on Exacerbation of Citrus Bacterial Spot.

Plant disease·2019
Same author

Metalaxyl-Resistant Isolates of Phytophthora nicotianae: Occurrence, Sensitivity, and Competitive Parasitic Ability on Citrus.

Plant disease·2019
Same author

Composted Municipal Waste Reduces Infection of Citrus Seedlings by Phytophthora nicotianae.

Plant disease·2019
Same author

Phytophthora Brown Rot of Citrus: Temperature and Moisture Effects on Infection, Sporangium Production, and Dispersal.

Plant disease·2019
Same author

Lack of Control of Citrus Canker by Induced Systemic Resistance Compounds.

Plant disease·2019
Same journal

Long-term outcomes of evolving treatment regimens in Ewing sarcoma survivors diagnosed 1970-1999: A report from the Childhood Cancer Survivor Study.

Cancer·2026
Same journal

Large-scale osteosarcoma sequencing reveals age-associated genomic architectures.

Cancer·2026
Same journal

EZH2 inhibitor tazemetostat voluntarily withdrawn from market.

Cancer·2026
Same journal

Nivolumab and chemotherapy combination approved for previously untreated Hodgkin lymphoma.

Cancer·2026
Same journal

Most older patients with advanced cancer prioritize QOL over extending survival: A secondary analysis of the GAP70+ trial found that among adults aged 70 and older with advanced, noncurable cancer, nearly three-quarters prioritized maintaining QOL.

Cancer·2026
Same journal

Real-world safety, prognostic, and design considerations in ketogenic diet trials for pancreatic cancer.

Cancer·2026
See all related articles

Area of Science:

  • Dermatopathology
  • Surgical Oncology
  • Oncology

Background:

  • Pilomatrix carcinoma is an exceedingly rare malignant neoplasm, representing a malignant variant of pilomatrixoma.
  • This study presents findings from 20 pilomatrix carcinoma cases and a review of existing literature.

Purpose of the Study:

  • To characterize the clinical and histological features of pilomatrix carcinoma.
  • To evaluate the treatment outcomes and prognostic factors associated with pilomatrix carcinoma.

Main Methods:

  • Retrospective review of 20 pilomatrix carcinoma cases from the Armed Forces Institute of Pathology.
  • Analysis of clinical data, histological features (hematoxylin and eosin, special stains), and follow-up information.

Main Results:

Related Experiment Videos

  • Pilomatrix carcinomas typically present as asymptomatic dermal/subcutaneous masses on the posterior neck/back, predominantly in middle-aged men (4:1 M:F ratio).
  • Histology shows atypical basaloid cells with infiltration, often with squamous differentiation, necrosis, and calcification.
  • Local recurrence occurred in 59% of patients, with metastasis and death observed in some cases, linked to greater anaplasia and deep infiltration.

Conclusions:

  • Pilomatrix carcinomas are locally aggressive with a high recurrence rate, especially after incomplete excision.
  • Prognosis is influenced by tumor anaplasia and depth of invasion.
  • Wide surgical excision is the primary treatment modality; the role of radiation therapy requires further investigation.