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Complex karyotypic abnormalities including t(8;22) in a patient with chronic lymphocytic leukemia
1Jiangsu Institute of Hematology, Leukemia Research Unit, Suzhou, Peoples Republic of China.
Cancer Genetics and Cytogenetics
|February 1, 1993
Abstract:
The case of a 49-year-old Chinese man with B-cell chronic lymphocytic leukemia (B-CLL) is presented. Complex karyotypic abnormalities comprising t(8;22)(q24;q11), trisomy 7, a deletion of 11q, and two small marker chromosomes were observed in PWM-stimulated cultures of his peripheral blood cells. To our knowledge, this is the first report of a t(8;22) in CLL.