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'Bioluminescent' Reporter Phage for the Detection of Category A Bacterial Pathogens
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Covalently immobilized DNA plate for luminometric DNA-DNA hybridization to identify viridans streptococci in under 2

S Adnan1, N Li, H Miura

  • 1Department of Microbiology, Gifu University, School of Medicine, Japan.

FEMS Microbiology Letters
|January 15, 1993
PubMed

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...