Chronicled metastases in a hamster melanoma

Fortner's Melanotic Melanoma No 1 was inoculated into the right hindfoot of 86 golden hamsters. Three, 7, 14, 21, and 28 days after inoculation, groups of hamsters underwent amputations at the ipsilateral hindhip to determine when pulmonary metastases initially occur. Upon subsequent sacrifice of the hamsters, pulmonary metastases were found to occur initially within 14 days of tumor inoculation.