Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Long-term sweat collection using salt-impregnated pads

M Phillips, R E Vandervoort, C E Becker

    The Journal of Investigative Dermatology
    |April 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The interleukin-6 promoter polymorphism in Gaucher disease: a new modifier gene?

    QJM : monthly journal of the Association of Physicians·2003
    Same author

    Fibrin sealants in supporting surgical techniques: strength in factor XIII.

    Cardiovascular surgery (London, England)·2003
    Same author

    Effect of oxygen on breath markers of oxidative stress.

    The European respiratory journal·2003
    Same author

    A multi-project systems approach to developing community trust and building capacity.

    Journal of public health management and practice : JPHMP·2002
    Same author

    Developing community capacity and improving health in African American communities.

    The American journal of the medical sciences·2002
    Same author

    Developing community capacity and improving health in African American communities.

    The American journal of the medical sciences·2001
    Same journal

    Reducing plastic waste in skin-model research: Sustainable packaging as a practical first step.

    The Journal of investigative dermatology·2026
    Same journal

    Modern serum proteomics in precision medicine: Toward disease stratification and predictive, proactive treatment strategies.

    The Journal of investigative dermatology·2026
    Same journal

    An Integrated Skin Cell Atlas Decodes the Pilosebaceous Unit.

    The Journal of investigative dermatology·2026
    Same journal

    Residual CSB activity explains mild UV-sensitive syndrome phenotype caused by CSB mutations.

    The Journal of investigative dermatology·2026
    Same journal

    Charting a new melanoma risk factor: Satellite Naevus Prevalence in High-Risk and Population-Based Cohorts.

    The Journal of investigative dermatology·2026
    Same journal

    Human keratinocytes and fibroblasts coordinate early cutaneous innate defenses against Candida auris.

    The Journal of investigative dermatology·2026
    See all related articles

    A new method using salt-impregnated pads collects sweat steadily for 8 days, aiding drug pharmacokinetics research. This technique offers a convenient tool for long-term sweat collection at a consistent rate.

    Area of Science:

    • Physiology
    • Biomedical Engineering

    Background:

    • Accurate sweat collection is crucial for pharmacokinetic studies.
    • Existing methods may not provide consistent sweat rates over extended periods.

    Purpose of the Study:

    • To develop and evaluate a novel technique for steady-state sweat collection over 8 days.
    • To assess the efficacy of salt-impregnated absorbent pads for prolonged sweat acquisition.

    Main Methods:

    • Three subjects wore absorbent pads (plain cotton vs. sodium chloride-impregnated) under waterproof dressings for 8 days.
    • Pads were applied to a defined skin area (2 cm x 2 cm) and replaced daily to measure sweat uptake.
    • Uptake was quantified by pad weight change over time.

    Main Results:

    Related Experiment Videos

    • Plain cotton pads reached a sweat uptake plateau within 2-3 days.
    • Salt-impregnated pads demonstrated continuous, steady sweat collection for the full 8-day study duration.
    • Mean collection rate for salt-impregnated pads was 0.79 mg/cm²/hr (SD = 0.16).

    Conclusions:

    • Salt-impregnated pads provide a reliable method for sustained sweat collection.
    • This technique facilitates long-term pharmacokinetic studies of drugs in sweat.
    • The osmotic gradient across the skin may influence sweat collection efficiency.