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Related Experiment Video

Updated: Jul 1, 2026

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
11:54

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Hyposmia in allergic rhinitis

B J Cowart1, K Flynn-Rodden, S J McGeady

  • 1Monell Chemical Senses Center, Philadelphia, PA 19104.

The Journal of Allergy and Clinical Immunology
|March 1, 1993
PubMed
Summary
This summary is machine-generated.

Allergic rhinitis is linked to smell loss, with 23.1% of patients experiencing hyposmia. Sinusitis or nasal polyps may cause this smell dysfunction in allergy sufferers.

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Area of Science:

  • Otolaryngology
  • Allergology
  • Olfactory Science

Background:

  • The link between nasal allergy and smell dysfunction (hyposmia) is recognized but not well-quantified.
  • Prevalence and underlying causes of hyposmia in allergic rhinitis remain unclear.

Purpose of the Study:

  • To determine the prevalence of hyposmia in individuals with allergic rhinitis.
  • To investigate the contribution of nasal congestion and associated conditions like sinusitis or nasal polyps to hyposmia in allergic rhinitis.

Main Methods:

  • Olfactory thresholds were measured using phenylethyl alcohol in 91 allergic rhinitis patients and 80 controls.
  • Total nasal resistance was assessed to evaluate nasal congestion's role.
  • Clinical and radiographic data were analyzed for sinusitis or nasal polyps.

Main Results:

  • Allergic rhinitis patients had significantly higher olfactory thresholds (indicating poorer smell) than controls (p < 0.001).
  • 23.1% of allergic patients exhibited clinically significant smell loss.
  • While nasal resistance was higher in patients, it did not correlate with olfactory threshold. Sinusitis or nasal polyps were significantly associated with hyposmia (p < 0.006).

Conclusions:

  • Hyposmia is a significant issue in allergic rhinitis patients, suggesting it's a major cause of smell disorders.
  • Sinusitis and/or nasal polyps are likely underlying factors in many cases of allergy-related smell loss.