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Anabolic steroids

K J Brower1

  • 1Department of Psychiatry, University of Michigan, Ann Arbor.

The Psychiatric Clinics of North America
|March 1, 1993
PubMed
Summary
This summary is machine-generated.

Anabolic-androgenic steroids (AASs) illicitly used for performance can alter mood and behavior, posing serious health risks. Cessation may reverse some effects, but fatalities from liver disease, heart attacks, and cancer are reported.

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Area of Science:

  • Endocrinology
  • Toxicology
  • Psychiatry

Background:

  • Anabolic-androgenic steroids (AASs) are frequently misused for performance and aesthetic enhancement.
  • Evidence suggests AASs impact mood and behavior, alongside physical changes.
  • Adverse effects are common, with severe outcomes reported.

Purpose of the Study:

  • To review the known effects of AASs on mood and behavior.
  • To highlight the risks associated with illicit AAS use.
  • To inform clinicians on identifying and managing AAS users.

Main Methods:

  • Literature review of reported adverse effects and clinical observations.
  • Analysis of risks associated with specific patterns of illicit AAS use.
  • Discussion of diagnostic and therapeutic considerations.

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Main Results:

  • Illicit AAS use is associated with significant mood and behavioral alterations.
  • High-risk usage patterns (high doses, polydrug use, non-sterile injections) increase adverse event probability.
  • Fatalities, including suicide, homicide, liver disease, cardiovascular events, and cancer, have been infrequently reported.

Conclusions:

  • Clinicians should suspect AAS use in individuals presenting with adverse consequences.
  • Laboratory testing aids in AAS detection and consequence assessment.
  • Treatment requires addressing substance abuse principles and the user's focus on physical attributes.