Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Increased depression in multiple sclerosis patients. A meta-analysis

D S Schubert1, R H Foliart

  • 1Case Western Reserve University School of Medicine, Cleveland, OH.

Psychosomatics
|March 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Utility of clinical characteristics in identifying depression in geriatric ED patients.

The American journal of emergency medicine·1999
Same author

A five-year study on the interactive effects of depression and physical illness on psychiatric unit length of stay.

Psychosomatic medicine·1999
Same author

Depressed mood and survival in seriously ill hospitalized adults. The SUPPORT Investigators.

Archives of internal medicine·1998
Same author

Recognition of depression in geriatric ED patients by emergency physicians.

Annals of emergency medicine·1997
Same author

Depression in geriatric ED patients: prevalence and recognition.

Annals of emergency medicine·1997
Same author

Sex-of-sibling effects: a review. Part II. Personality and mental and physical health.

Advances in child development and behavior·1996

Multiple sclerosis (MS) patients experience significantly higher rates of depression compared to the general population. This finding synthesizes evidence from multiple controlled studies, highlighting a critical mental health concern for individuals with MS.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Psychology

Background:

  • Conflicting clinical reports and experimental data exist regarding depression prevalence in multiple sclerosis (MS).
  • Recent reviews indicate a scarcity of controlled studies investigating depression in MS patients.
  • Depression is a common comorbidity impacting quality of life and disease management.

Purpose of the Study:

  • To comprehensively analyze and synthesize existing research comparing depression levels in MS patients versus control groups.
  • To provide a statistically robust conclusion on the association between MS and depression.

Main Methods:

  • A systematic literature search was conducted to identify relevant comparative studies.
  • Six controlled studies comparing depression in MS patients and non-MS comparison groups were included.

Related Experiment Videos

  • A meta-analysis was performed to combine the findings of the selected studies.

    • Main Results:

    • The meta-analysis revealed a statistically significant difference in depression levels.
    • MS patients exhibited markedly higher depression scores compared to individuals in the comparison groups.
    • This finding remained consistent across the combined data from the six studies.

    Conclusions:

    • Multiple sclerosis patients are significantly more prone to depression than individuals without the condition.
    • The findings underscore the importance of screening for and managing depression in MS care.
    • Further research may explore underlying mechanisms and effective interventions for depression in MS.