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Anthelmintic activity of pyrazinothiadiazine dioxide derivatives
1Instituto de Química Médica, Consejo Superior de Investigaciones Cientificas, Madrid, Spain.
Arzneimittel-Forschung
|February 1, 1993
Abstract:
In a search for new anthelmintic compounds, some pyrazinothiadiazine dioxide derivatives were synthesized. Their anthelmintic activity was tested against larva and preadult stages of Trichinella spiralis. The mode of action and acute toxicity of these compounds were investigated. Structure-activity relationships are discussed.