Microphthalmos with orbital cyst: a clinicopathological report

Area of Science:

• Ophthalmology
• Developmental Biology
• Pathology

Background:

• Microphthalmos is a congenital condition characterized by abnormally small eyes.
• Orbital cysts can occur in conjunction with microphthalmos, presenting complex clinical challenges.
• Coloboma, a defect in ocular development, can manifest in various forms and affect different stages of embryonic eye formation.

Purpose of the Study:

• To describe the clinical and histopathological findings of a rare case of microphthalmos with an orbital cyst.
• To emphasize the significance of bilateral coloboma as a clinical indicator of embryonic ocular development interference.

Main Methods:

• Clinical examination of the patient's ocular and orbital structures.
• Histopathological analysis of tissue samples to determine the nature of the cyst and associated anomalies.
• Review of relevant literature on microphthalmos, orbital cysts, and coloboma.

Main Results:

• The case presented with microphthalmos and a significant orbital cyst.
• Bilateral coloboma was a prominent clinical feature, observed in both eyes.
• Histopathological findings confirmed the diagnosis and provided insights into the developmental anomalies.

Conclusions:

• Microphthalmos with orbital cyst is a complex condition requiring thorough clinical and pathological evaluation.
• Bilateral coloboma serves as a crucial marker for understanding the timing and nature of embryonic ocular developmental disturbances.
• This case underscores the importance of recognizing diverse presentations of congenital eye anomalies.