Carotid endarterectomy for asymptomatic patients. Assessing results of a quantitative synthesis
J C Langenbrunner1, P M Wortman, W H Yeaton
1Executive Office of the President, Office of Management and Budget, Washington, DC 20503.
Abstract:
Carotid endarterectomy (CE) surgery for asymptomatic patients remains controversial despite hundreds of published studies and recent randomized trials. Safety and efficacy are assessed using a quantitative synthesis method derived from meta-analysis and a "critical multiplist" inference approach. In addition, multivariate analyses reveal that use of a surgical shunt could further improve CE outcomes. Methods are examined for both their "confirmatory" and "exploratory" value.
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