Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Invasive aspergilloma of the skull base

D J Breen1, A G Clifton, P Wilkins

  • 1Department of Neuroradiology, Atkinson Morley's Hospital, London, UK.

Neuroradiology
|January 1, 1993
PubMed
Summary

Nasal Aspergillus infections can rarely cause benign, locally invasive skull base disease. This case highlights extensive infection leading to bilateral proptosis and anterior cranial fossa invasion.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

IO1-UK: a cross-sectional study to re-evaluate the provision of interventional oncology services across the United Kingdom.

Clinical radiology·2026
Same author

Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment.

Physical review letters·2024
Same author

Lawson Criterion for Ignition Exceeded in an Inertial Fusion Experiment.

Physical review letters·2022
Same author

Pharmacokinetics of intravenous and oral administration of enrofloxacin to the late-term pregnant and non-pregnant mares.

Equine veterinary journal·2019
Same author

Safety of percutaneous renal cryoablation: an international multicentre experience from the EuRECA retrospective percutaneous database.

European radiology·2019
Same author

Diffusion of enrofloxacin to pregnancy fluids and effects on fetal cartilage after intravenous administration to late pregnant mares.

Equine veterinary journal·2018

Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Infectious Diseases

Background:

  • Aspergillus infections typically manifest as localized disease in immunocompetent individuals.
  • Rarely, Aspergillus can cause benign, locally invasive skull base disease originating from the sinonasal tract.

Observation:

  • A case of extensive Aspergillus infection originating in the nasal cavity and paranasal sinuses is presented.
  • The infection led to significant local invasion, causing bilateral proptosis and involvement of the anterior cranial fossa.

Findings:

  • The sinonasal Aspergillus infection demonstrated locally invasive behavior, extending to the skull base.
  • Radiological and pathological findings confirmed extensive disease with orbital and intracranial involvement.

Implications:

  • This case underscores the importance of considering sinonasal Aspergillus as a cause of skull base and orbital complications.
  • Early diagnosis and appropriate management are crucial to prevent severe morbidity associated with locally invasive fungal infections.

Related Experiment Videos